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Differences of Uric Acid Transporters Carrying Extracellular Vesicles in the Urine from Uric Acid and Calcium Stone Formers and Non-Stone Formers

Background: Low urine pH and volume are established risk factors for uric acid (UA) stone disease (UASD). Renal tubular epithelial cells exposed to an acidic pH and/or UA crystals can shed extracellular vesicles (EVs) into the tubular fluid, and these EVs may be a pathogenic biomarker of UASD. Metho...

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Detalles Bibliográficos
Autores principales: Lin, Zhijian, Jayachandran, Muthuvel, Haskic, Zejfa, Kumar, Sanjay, Lieske, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456222/
https://www.ncbi.nlm.nih.gov/pubmed/36077407
http://dx.doi.org/10.3390/ijms231710010