p53 Controls Meiotic Prophase Progression and Crossover Formation

Meiosis initiates with the formation of double strand breaks (DSBs) throughout the genome. To avoid genomic instability, these DSBs need to be correctly repaired by homologous recombination. Surveillance mechanisms involving the DNA damage response (DDR) pathway ATM-CHK2-p53 can detect the persisten...

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Detalles Bibliográficos
Autores principales: Marcet-Ortega, Marina, Maldonado-Linares, Andros, López-Panadés, Maria, Roig, Ignasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456223/
https://www.ncbi.nlm.nih.gov/pubmed/36077210
http://dx.doi.org/10.3390/ijms23179818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456223/
https://www.ncbi.nlm.nih.gov/pubmed/36077210
http://dx.doi.org/10.3390/ijms23179818

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