Caffeine Inhibits NLRP3 Inflammasome Activation by Downregulating TLR4/MAPK/NF-κB Signaling Pathway in an Experimental NASH Model

Caffeine elicits protective effects against liver diseases, such as NASH; however, its mechanism of action involving the pyrin domain-containing-3 (NLRP3) inflammasome signaling pathway remains to be elucidated. This study aimed to evaluate the effect of caffeine on the NLRP3 inflammasome signaling...

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Detalles Bibliográficos
Autores principales: Vargas-Pozada, Eduardo E., Ramos-Tovar, Erika, Rodriguez-Callejas, Juan D., Cardoso-Lezama, Irina, Galindo-Gómez, Silvia, Talamás-Lara, Daniel, Vásquez-Garzón, Verónica Rocío, Arellanes-Robledo, Jaime, Tsutsumi, Víctor, Villa-Treviño, Saúl, Muriel, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456282/
https://www.ncbi.nlm.nih.gov/pubmed/36077357
http://dx.doi.org/10.3390/ijms23179954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456282/
https://www.ncbi.nlm.nih.gov/pubmed/36077357
http://dx.doi.org/10.3390/ijms23179954

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