Synthesis of 4-Hydroxyquinolines as Potential Cytotoxic Agents †

The synthesis of alkyl 2-(4-hydroxyquinolin-2-yl) acetates and 1-phenyl-4-(phenylamino)pyridine-2,6(1H,3H)-dione was optimised. Starting from 4-hydroxyquinolines (4HQs), aminomethylation was carried out via the modified Mannich reaction (mMr) applying formaldehyde and piperidine, but a second parafo...

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Detalles Bibliográficos
Autores principales: Csuvik, Oszkár, Szemerédi, Nikoletta, Spengler, Gabriella, Szatmári, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456289/
https://www.ncbi.nlm.nih.gov/pubmed/36077085
http://dx.doi.org/10.3390/ijms23179688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456289/
https://www.ncbi.nlm.nih.gov/pubmed/36077085
http://dx.doi.org/10.3390/ijms23179688

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