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Synthesis of 4-Hydroxyquinolines as Potential Cytotoxic Agents †

The synthesis of alkyl 2-(4-hydroxyquinolin-2-yl) acetates and 1-phenyl-4-(phenylamino)pyridine-2,6(1H,3H)-dione was optimised. Starting from 4-hydroxyquinolines (4HQs), aminomethylation was carried out via the modified Mannich reaction (mMr) applying formaldehyde and piperidine, but a second parafo...

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Detalles Bibliográficos
Autores principales:	Csuvik, Oszkár, Szemerédi, Nikoletta, Spengler, Gabriella, Szatmári, István
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456289/ https://www.ncbi.nlm.nih.gov/pubmed/36077085 http://dx.doi.org/10.3390/ijms23179688

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