Development of the Method for Nusinersen and Its Metabolites Identification in the Serum Samples of Children Treated with Spinraza for Spinal Muscular Atrophy

The application of oligonucleotides as drugs for different genetic diseases is increasing rapidly. Since 2016 they are used during spinal muscular atrophy treatment with the use of nusinersen oligonucleotide. The purpose of this study was to improve methods for the analysis of serum samples of patie...

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Detalles Bibliográficos
Autores principales: Studzińska, Sylwia, Mazurkiewicz-Bełdzińska, Maria, Buszewski, Bogusław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456300/
https://www.ncbi.nlm.nih.gov/pubmed/36077568
http://dx.doi.org/10.3390/ijms231710166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456300/
https://www.ncbi.nlm.nih.gov/pubmed/36077568
http://dx.doi.org/10.3390/ijms231710166

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