A Therapeutic Perspective of HDAC8 in Different Diseases: An Overview of Selective Inhibitors

Histone deacetylases (HDACs) are epigenetic enzymes which participate in transcriptional repression and chromatin condensation mechanisms by removing the acetyl moiety from acetylated ε-amino group of histone lysines and other non-histone proteins. In recent years, HDAC8, a class I HDAC, has emerged...

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Detalles Bibliográficos
Autores principales: Fontana, Anna, Cursaro, Ilaria, Carullo, Gabriele, Gemma, Sandra, Butini, Stefania, Campiani, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456347/
https://www.ncbi.nlm.nih.gov/pubmed/36077415
http://dx.doi.org/10.3390/ijms231710014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456347/
https://www.ncbi.nlm.nih.gov/pubmed/36077415
http://dx.doi.org/10.3390/ijms231710014

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