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Staphylococcus aureus Exfoliative Toxin E, Oligomeric State and Flip of P186: Implications for Its Action Mechanism

Staphylococcal exfoliative toxins (ETs) are glutamyl endopeptidases that specifically cleave the Glu381-Gly382 bond in the ectodomains of desmoglein 1 (Dsg1) via complex action mechanisms. To date, four ETs have been identified in different Staphylococcus aureus strains and ETE is the most recently...

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Detalles Bibliográficos
Autores principales: Gismene, Carolina, Hernández González, Jorge Enrique, Santisteban, Angela Rocio Niño, Ziem Nascimento, Andrey Fabricio, dos Santos Cunha, Lucas, de Moraes, Fábio Rogério, de Oliveira, Cristiano Luis Pinto, Oliveira, Caio C., Jocelan Scarin Provazzi, Paola, Pascutti, Pedro Geraldo, Arni, Raghuvir Krishnaswamy, Barros Mariutti, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456352/
https://www.ncbi.nlm.nih.gov/pubmed/36077258
http://dx.doi.org/10.3390/ijms23179857