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Using a Polygenic Score to Predict the Risk of Developing Primary Osteoporosis

Osteoporosis (OP) is a multifactorial bone disease belonging to the metabolic osteopathies group. Using the polygenic score (PGS) approach, we combined the effects of bone mineral density (BMD) DNA loci, affecting osteoporosis pathogenesis, based on GEFOS/GENOMOS consortium GWAS meta-analysis. We de...

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Detalles Bibliográficos
Autores principales: Yalaev, Bulat, Tyurin, Anton, Prokopenko, Inga, Karunas, Aleksandra, Khusnutdinova, Elza, Khusainova, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456390/
https://www.ncbi.nlm.nih.gov/pubmed/36077420
http://dx.doi.org/10.3390/ijms231710021