Alpha-Synuclein: The Spark That Flames Dopaminergic Neurons, In Vitro and In Vivo Evidence

Mitochondria, α-syn fibrils and the endo-lysosomal system are key players in the pathophysiology of Parkinson’s disease. The toxicity of α-syn is amplified by cell-to-cell transmission and aggregation of endogenous species in newly invaded neurons. Toxicity of α-syn PFF was investigated using primar...

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Detalles Bibliográficos
Autores principales: Henriques, Alexandre, Rouvière, Laura, Giorla, Elodie, Farrugia, Clémence, El Waly, Bilal, Poindron, Philippe, Callizot, Noëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456396/
https://www.ncbi.nlm.nih.gov/pubmed/36077253
http://dx.doi.org/10.3390/ijms23179864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456396/
https://www.ncbi.nlm.nih.gov/pubmed/36077253
http://dx.doi.org/10.3390/ijms23179864

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