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Alpha-Synuclein: The Spark That Flames Dopaminergic Neurons, In Vitro and In Vivo Evidence

Mitochondria, α-syn fibrils and the endo-lysosomal system are key players in the pathophysiology of Parkinson’s disease. The toxicity of α-syn is amplified by cell-to-cell transmission and aggregation of endogenous species in newly invaded neurons. Toxicity of α-syn PFF was investigated using primar...

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Detalles Bibliográficos
Autores principales:	Henriques, Alexandre, Rouvière, Laura, Giorla, Elodie, Farrugia, Clémence, El Waly, Bilal, Poindron, Philippe, Callizot, Noëlle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456396/ https://www.ncbi.nlm.nih.gov/pubmed/36077253 http://dx.doi.org/10.3390/ijms23179864

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