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Sodium-Calcium Exchanger 2: A Pivotal Role in Oxaliplatin Induced Peripheral Neurotoxicity and Axonal Damage?

Oxaliplatin (OHP)-induced peripheral neurotoxicity (OIPN) is a frequent adverse event of colorectal cancer treatment. OIPN encompasses a chronic and an acute syndrome. The latter consists of transient axonal hyperexcitability, due to unbalance in Na(+) voltage-operated channels (Na(+)VOC). This lead...

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Detalles Bibliográficos
Autores principales: Ballarini, Elisa, Malacrida, Alessio, Rodriguez-Menendez, Virginia, Pozzi, Eleonora, Canta, Annalisa, Chiorazzi, Alessia, Monza, Laura, Semperboni, Sara, Meregalli, Cristina, Carozzi, Valentina Alda, Hashemi, Maryamsadat, Nicolini, Gabriella, Scuteri, Arianna, Housley, Stephen N., Cavaletti, Guido, Alberti, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456447/
https://www.ncbi.nlm.nih.gov/pubmed/36077454
http://dx.doi.org/10.3390/ijms231710063