Targeting Lineage-Specific Transcription Factors and Cytokines of the Th17/Treg Axis by Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone Attenuates TNBS-Induced Experimental Colitis

The pharmacotherapy of inflammatory bowel disease (IBD) is still not fully effective and safe. Attempts to search for new IBD drugs remain an incessant research aim. One of the novel approaches is targeting the developmental pathway molecules and effector cytokines of Th17/Treg axis. This study aime...

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Detalles Bibliográficos
Autores principales: Szandruk-Bender, Marta, Wiatrak, Benita, Dzimira, Stanisław, Merwid-Ląd, Anna, Szczukowski, Łukasz, Świątek, Piotr, Szeląg, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456461/
https://www.ncbi.nlm.nih.gov/pubmed/36077306
http://dx.doi.org/10.3390/ijms23179897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456461/
https://www.ncbi.nlm.nih.gov/pubmed/36077306
http://dx.doi.org/10.3390/ijms23179897

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