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Targeting the Mitochondrial Protein VDAC1 as a Potential Therapeutic Strategy in ALS

Impaired mitochondrial function has been proposed as a causative factor in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), caused by motor neuron degeneration. Mutations in superoxide dismutase (SOD1) cause ALS and SOD1 mutants were shown to interact with the voltage-depen...

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Detalles Bibliográficos
Autores principales: Shteinfer-Kuzmine, Anna, Argueti-Ostrovsky, Shirel, Leyton-Jaimes, Marcel F., Anand, Uttpal, Abu-Hamad, Salah, Zalk, Ran, Shoshan-Barmatz, Varda, Israelson, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456491/
https://www.ncbi.nlm.nih.gov/pubmed/36077343
http://dx.doi.org/10.3390/ijms23179946