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Targeting the Mitochondrial Protein VDAC1 as a Potential Therapeutic Strategy in ALS
Impaired mitochondrial function has been proposed as a causative factor in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), caused by motor neuron degeneration. Mutations in superoxide dismutase (SOD1) cause ALS and SOD1 mutants were shown to interact with the voltage-depen...
Autores principales: | Shteinfer-Kuzmine, Anna, Argueti-Ostrovsky, Shirel, Leyton-Jaimes, Marcel F., Anand, Uttpal, Abu-Hamad, Salah, Zalk, Ran, Shoshan-Barmatz, Varda, Israelson, Adrian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456491/ https://www.ncbi.nlm.nih.gov/pubmed/36077343 http://dx.doi.org/10.3390/ijms23179946 |
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