The Distinct Roles of LKB1 and AMPK in p53-Dependent Apoptosis Induced by Cisplatin

Liver kinase B1 (LKB1) is a serine/threonine protein kinase that acts as a key tumor suppressor protein by activating its downstream kinases, such as AMP-activated protein kinase (AMPK). However, the regulatory actions of LKB1 and AMPK on DNA damage response (DDR) remain to be explored. In this stud...

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Detalles Bibliográficos
Autores principales: Shimada, Tatsuya, Yabuki, Yohsuke, Noguchi, Takuya, Tsuchida, Mei, Komatsu, Ryuto, Hamano, Shuhei, Yamada, Mayuka, Ezaki, Yusuke, Hirata, Yusuke, Matsuzawa, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456506/
https://www.ncbi.nlm.nih.gov/pubmed/36077459
http://dx.doi.org/10.3390/ijms231710064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456506/
https://www.ncbi.nlm.nih.gov/pubmed/36077459
http://dx.doi.org/10.3390/ijms231710064

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