Effect of Delta and Omicron Mutations on the RBD-SD1 Domain of the Spike Protein in SARS-CoV-2 and the Omicron Mutations on RBD-ACE2 Interface Complex

The receptor-binding domain (RBD) is the essential part in the Spike-protein (S-protein) of SARS-CoV-2 virus that directly binds to the human ACE2 receptor, making it a key target for many vaccines and therapies. Therefore, any mutations at this domain could affect the efficacy of these treatments a...

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Detalles Bibliográficos
Autores principales: Ching, Wai-Yim, Adhikari, Puja, Jawad, Bahaa, Podgornik, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456519/
https://www.ncbi.nlm.nih.gov/pubmed/36077490
http://dx.doi.org/10.3390/ijms231710091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456519/
https://www.ncbi.nlm.nih.gov/pubmed/36077490
http://dx.doi.org/10.3390/ijms231710091

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