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Inhibition of Class I Histone Deacetylase Activity Blocks the Induction of TNFAIP3 Both Directly and Indirectly via the Suppression of Endogenous TNF-α

Histone deacetylase inhibitors (HDIs) are promising drugs for the treatment of inflammatory diseases. However, their therapeutical exploitation is slowed down by severe adverse manifestations that can hardly be foreseen, mainly due to incomplete knowledge of how HDIs impact the delicate balance of i...

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Detalles Bibliográficos
Autores principales: Schioppa, Tiziana, Nguyen, Hoang Oanh, Tiberio, Laura, Sozio, Francesca, Gaudenzi, Carolina, Passari, Mauro, Del Prete, Annalisa, Bosisio, Daniela, Salvi, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456523/
https://www.ncbi.nlm.nih.gov/pubmed/36077149
http://dx.doi.org/10.3390/ijms23179752