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Inhibition of Class I Histone Deacetylase Activity Blocks the Induction of TNFAIP3 Both Directly and Indirectly via the Suppression of Endogenous TNF-α
Histone deacetylase inhibitors (HDIs) are promising drugs for the treatment of inflammatory diseases. However, their therapeutical exploitation is slowed down by severe adverse manifestations that can hardly be foreseen, mainly due to incomplete knowledge of how HDIs impact the delicate balance of i...
Autores principales: | Schioppa, Tiziana, Nguyen, Hoang Oanh, Tiberio, Laura, Sozio, Francesca, Gaudenzi, Carolina, Passari, Mauro, Del Prete, Annalisa, Bosisio, Daniela, Salvi, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456523/ https://www.ncbi.nlm.nih.gov/pubmed/36077149 http://dx.doi.org/10.3390/ijms23179752 |
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