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NAD/NAMPT and mTOR Pathways in Melanoma: Drivers of Drug Resistance and Prospective Therapeutic Targets

Malignant melanoma represents the most fatal skin cancer due to its aggressive behavior and high metastatic potential. The introduction of BRAF/MEK inhibitors and immune-checkpoint inhibitors (ICIs) in the clinic has dramatically improved patient survival over the last decade. However, many patients...

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Detalles Bibliográficos
Autores principales: Indini, Alice, Fiorilla, Irene, Ponzone, Luca, Calautti, Enzo, Audrito, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456568/
https://www.ncbi.nlm.nih.gov/pubmed/36077374
http://dx.doi.org/10.3390/ijms23179985