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The E3 ubiquitin ligase HUWE1 acts through the N‐Myc‐DLL1‐NOTCH1 signaling axis to suppress glioblastoma progression

BACKGROUND: Elucidation of the post‐transcriptional modification has led to novel strategies to treat intractable tumors, especially glioblastoma (GBM). The ubiquitin‐proteasome system (UPS) mediates a reversible, stringent and stepwise post‐translational modification which is closely associated wit...

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Detalles Bibliográficos
Autores principales: Yuan, Ye, Wang, Li‐Hong, Zhao, Xian‐Xian, Wang, Jiao, Zhang, Meng‐Si, Ma, Qing‐Hua, Wei, Sen, Yan, Ze‐Xuan, Cheng, Yue, Chen, Xiao‐Qing, Zou, Hong‐Bo, Ge, Jia, Wang, Yan, Zhang, Xia, Cui, You‐Hong, Luo, Tao, Bian, Xiu‐Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456703/
https://www.ncbi.nlm.nih.gov/pubmed/35848447
http://dx.doi.org/10.1002/cac2.12334