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ER-resident STIM1/2 couples Ca(2+) entry by NMDA receptors to pannexin-1 activation

Pannexin-1 (Panx1) is a large-pore ion and solute permeable channel highly expressed in the nervous system, where it subserves diverse processes, including neurite outgrowth, dendritic spine formation, and N-methyl D-aspartate (NMDA) receptor (NMDAR)-dependent plasticity. Moreover, Panx1 dysregulati...

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Detalles Bibliográficos
Autores principales: Patil, Chetan S., Li, Hongbin, Lavine, Natalie E., Shi, Ruoyang, Bodalia, Ankur, Siddiqui, Tabrez J., Jackson, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456761/
https://www.ncbi.nlm.nih.gov/pubmed/36037373
http://dx.doi.org/10.1073/pnas.2112870119