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3D chromatin remodeling potentiates transcriptional programs driving cell invasion

The contribution of deregulated chromatin architecture, including topologically associated domains (TADs), to cancer progression remains ambiguous. CCCTC-binding factor (CTCF) is a central regulator of higher-order chromatin structure that undergoes copy number loss in over half of all breast cancer...

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Detalles Bibliográficos
Autores principales: Lebeau, Benjamin, Jangal, Maïka, Zhao, Tiejun, Wong, Cheng Kit, Wong, Nolan, Cañedo, Eduardo Cepeda, Hébert, Steven, Aguilar-Mahecha, Adriana, Chabot, Catherine, Buchanan, Marguerite, Catterall, Rachel, McCaffrey, Luke, Deblois, Geneviève, Kleinman, Claudia, Park, Morag, Basik, Mark, Witcher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457068/
https://www.ncbi.nlm.nih.gov/pubmed/36037342
http://dx.doi.org/10.1073/pnas.2203452119