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3D chromatin remodeling potentiates transcriptional programs driving cell invasion
The contribution of deregulated chromatin architecture, including topologically associated domains (TADs), to cancer progression remains ambiguous. CCCTC-binding factor (CTCF) is a central regulator of higher-order chromatin structure that undergoes copy number loss in over half of all breast cancer...
Autores principales: | Lebeau, Benjamin, Jangal, Maïka, Zhao, Tiejun, Wong, Cheng Kit, Wong, Nolan, Cañedo, Eduardo Cepeda, Hébert, Steven, Aguilar-Mahecha, Adriana, Chabot, Catherine, Buchanan, Marguerite, Catterall, Rachel, McCaffrey, Luke, Deblois, Geneviève, Kleinman, Claudia, Park, Morag, Basik, Mark, Witcher, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457068/ https://www.ncbi.nlm.nih.gov/pubmed/36037342 http://dx.doi.org/10.1073/pnas.2203452119 |
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