Multimodal cotranslational interactions direct assembly of the human multi-tRNA synthetase complex

Amino acid ligation to cognate transfer RNAs (tRNAs) is catalyzed by aminoacyl-tRNA synthetases (aaRSs)—essential interpreters of the genetic code during translation. Mammalian cells harbor 20 cytoplasmic aaRSs, out of which 9 (in 8 proteins), with 3 non-aaRS proteins, AIMPs 1 to 3, form the ∼1.25-M...

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Detalles Bibliográficos
Autores principales: Khan, Krishnendu, Long, Briana, Gogonea, Valentin, Deshpande, Gauravi M., Vasu, Kommireddy, Fox, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457175/
https://www.ncbi.nlm.nih.gov/pubmed/36037331
http://dx.doi.org/10.1073/pnas.2205669119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457175/
https://www.ncbi.nlm.nih.gov/pubmed/36037331
http://dx.doi.org/10.1073/pnas.2205669119

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