Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3

Calcific aortic valve disease (CAVD) is common in people over the age of 65. Progressive valvular calcification is a characteristic of CAVD and due to chronic inflammation in aortic valve interstitial cells (AVICs) resulting in CAVD progression. IL-38 is a naturally occurring anti-inflammatory cytok...

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Detalles Bibliográficos
Autores principales: The, Erlinda, de Graaf, Dennis M., Zhai, Yufeng, Yao, Qingzhou, Ao, Lihua, Fullerton, David A., Dinarello, Charles A., Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457240/
https://www.ncbi.nlm.nih.gov/pubmed/36037361
http://dx.doi.org/10.1073/pnas.2202577119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457240/
https://www.ncbi.nlm.nih.gov/pubmed/36037361
http://dx.doi.org/10.1073/pnas.2202577119

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