USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer

Clear cell renal cell carcinoma (ccRCC) is characterized by the loss of tumor suppressor Von Hippel Lindau (VHL) function. VHL is the component of an E3 ligase complex that promotes the ubiquitination and degradation of hypoxia inducible factor α (HIF-α) (including HIF1α and HIF2α) and Zinc Fingers...

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Detalles Bibliográficos
Autores principales: Xie, Haibiao, Zhou, Jin, Liu, Xijuan, Xu, Yawei, Hepperla, Austin J., Simon, Jeremy M., Wang, Tao, Yao, Hongwei, Liao, Chengheng, Baldwin, Albert S., Gong, Kan, Zhang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457248/
https://www.ncbi.nlm.nih.gov/pubmed/36037364
http://dx.doi.org/10.1073/pnas.2119854119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457248/
https://www.ncbi.nlm.nih.gov/pubmed/36037364
http://dx.doi.org/10.1073/pnas.2119854119

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