Cholesterol inhibits human voltage-gated proton channel hHv1

Although human sperm is morphologically mature in the epididymis, it cannot fertilize eggs before capacitation. Cholesterol efflux from the sperm plasma membrane is a key molecular event essential for cytoplasmic alkalinization and hyperactivation, but the underlying mechanism remains unclear. The h...

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Detalles Bibliográficos
Autores principales: Han, Shuo, Chu, Xiang-Ping, Goodson, Ryan, Gamel, Prae, Peng, Sophia, Vance, Joshua, Wang, Shizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457259/
https://www.ncbi.nlm.nih.gov/pubmed/36037383
http://dx.doi.org/10.1073/pnas.2205420119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457259/
https://www.ncbi.nlm.nih.gov/pubmed/36037383
http://dx.doi.org/10.1073/pnas.2205420119

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