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Cholesterol inhibits human voltage-gated proton channel hHv1

Although human sperm is morphologically mature in the epididymis, it cannot fertilize eggs before capacitation. Cholesterol efflux from the sperm plasma membrane is a key molecular event essential for cytoplasmic alkalinization and hyperactivation, but the underlying mechanism remains unclear. The h...

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Detalles Bibliográficos
Autores principales:	Han, Shuo, Chu, Xiang-Ping, Goodson, Ryan, Gamel, Prae, Peng, Sophia, Vance, Joshua, Wang, Shizhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457259/ https://www.ncbi.nlm.nih.gov/pubmed/36037383 http://dx.doi.org/10.1073/pnas.2205420119

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