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Hippo signaling cofactor, WWTR1, at the crossroads of human trophoblast progenitor self-renewal and differentiation

Healthy progression of human pregnancy relies on cytotrophoblast (CTB) progenitor self-renewal and its differentiation toward multinucleated syncytiotrophoblasts (STBs) and invasive extravillous trophoblasts (EVTs). However, the underlying molecular mechanisms that fine-tune CTB self-renewal or dire...

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Detalles Bibliográficos
Autores principales: Ray, Soma, Saha, Abhik, Ghosh, Ananya, Roy, Namrata, Kumar, Ram P., Meinhardt, Gudrun, Mukerjee, Abhirup, Gunewardena, Sumedha, Kumar, Rajnish, Knöfler, Martin, Paul, Soumen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457323/
https://www.ncbi.nlm.nih.gov/pubmed/36037374
http://dx.doi.org/10.1073/pnas.2204069119