Mitochondrial outer membrane protein FUNDC2 promotes ferroptosis and contributes to doxorubicin-induced cardiomyopathy

Ferroptosis is an iron-dependent programmed necrosis characterized by glutathione (GSH) depletion and lipid peroxidation (LPO). Armed with both the pro- and antiferroptosis machineries, mitochondria play a central role in ferroptosis. However, how mitochondria sense the stress to activate ferroptosi...

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Detalles Bibliográficos
Autores principales: Ta, Na, Qu, Chuanren, Wu, Hao, Zhang, Di, Sun, Tiantian, Li, Yanjun, Wang, Jun, Wang, Xiaohui, Tang, Tieshan, Chen, Quan, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457330/
https://www.ncbi.nlm.nih.gov/pubmed/36037337
http://dx.doi.org/10.1073/pnas.2117396119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457330/
https://www.ncbi.nlm.nih.gov/pubmed/36037337
http://dx.doi.org/10.1073/pnas.2117396119

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