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Mapping the per-residue surface electrostatic potential of CAPRIN1 along its phase-separation trajectory
Electrostatic interactions and charge balance are important for the formation of biomolecular condensates involving proteins and nucleic acids. However, a detailed, atomistic picture of the charge distribution around proteins during the phase-separation process is lacking. Here, we use solution NMR...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457416/ https://www.ncbi.nlm.nih.gov/pubmed/36040869 http://dx.doi.org/10.1073/pnas.2210492119 |