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Structure–Activity Relationship Development Efforts towards Peripherally Selective Analogs of the Cannabinoid Receptor Partial Agonist BAY 59-3074

Selective modulation of peripheral cannabinoid receptors (CBRs) has potential therapeutic applications in medical conditions, including obesity, diabetes, liver diseases, GI disorders and pain. While there have been considerable efforts to produce selective antagonists or full agonists of CBRs, ther...

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Detalles Bibliográficos
Autores principales: Amato, George, Vasukuttan, Vineetha, Harris, Danni, Laudermilk, Lucas, Lucitti, Jennifer, Runyon, Scott, Maitra, Rangan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457575/
https://www.ncbi.nlm.nih.gov/pubmed/36080443
http://dx.doi.org/10.3390/molecules27175672