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Synthesis of thia-Michael-Type Adducts between Naphthoquinones and N-Acetyl-L-Cysteine and Their Biological Activity

A series of naphthoquinones, namely, 1,4-naphthoquinone, menadione, plumbagin, juglone, naphthazarin, and lawsone, were reacted with N-acetyl-L-cysteine, and except for lawsone, which did not react, the related adducts were obtained. After the tuning of the solvent and reaction conditions, the react...

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Detalles Bibliográficos
Autores principales: Micheletti, Gabriele, Boga, Carla, Zalambani, Chiara, Farruggia, Giovanna, Esposito, Erika, Fiori, Jessica, Rizzardi, Nicola, Taddei, Paola, Di Foggia, Michele, Calonghi, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457610/
https://www.ncbi.nlm.nih.gov/pubmed/36080409
http://dx.doi.org/10.3390/molecules27175645