HLJ1 amplifies endotoxin-induced sepsis severity by promoting IL-12 heterodimerization in macrophages

Heat shock protein (HSP) 40 has emerged as a key factor in both innate and adaptive immunity, whereas the role of HLJ1, a molecular chaperone in HSP40 family, in modulating endotoxin-induced sepsis severity is still unclear. During lipopolysaccharide (LPS)-induced endotoxic shock, HLJ1 knockout mice...

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Detalles Bibliográficos
Autores principales: Luo, Wei-Jia, Yu, Sung-Liang, Chang, Chia-Ching, Chien, Min-Hui, Chang, Ya-Ling, Liao, Keng-Mao, Lin, Pei-Chun, Chung, Kuei-Pin, Chuang, Ya-Hui, Chen, Jeremy JW, Yang, Pan-Chyr, Su, Kang-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457701/
https://www.ncbi.nlm.nih.gov/pubmed/35983991
http://dx.doi.org/10.7554/eLife.76094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457701/
https://www.ncbi.nlm.nih.gov/pubmed/35983991
http://dx.doi.org/10.7554/eLife.76094

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