Development and Validation of a Highly Sensitive and Rapid LC-MS(3) Strategy to Determine Oxcarbazepine and Its Active Metabolite in the Serum of Patients with Epilepsy and Its Application in Therapeutic Drug Monitoring

A sensitive and rapid bioanalytical method based on the LC-triple-stage fragmentation (LC-MS(3)) strategy on a hybrid triple quadrupole-linear ion trap mass spectrometer in combination with protein precipitation extraction for sample pretreatment has been developed and validated for the simultaneous...

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Detalles Bibliográficos
Autores principales: Ji, Zhengchao, Li, Tingting, Zhao, Xin, Ma, Wei, Li, Yanyan, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457704/
https://www.ncbi.nlm.nih.gov/pubmed/36080439
http://dx.doi.org/10.3390/molecules27175670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457704/
https://www.ncbi.nlm.nih.gov/pubmed/36080439
http://dx.doi.org/10.3390/molecules27175670

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