Ajuforrestin A, an Abietane Diterpenoid from Ajuga ovalifolia var. calanthe, Induces A549 Cell Apoptosis by Targeting SHP2

The Src-homology 2 domain-containing phosphatase 2 (SHP2), which is encoded by PTPN11, participates in many cellular signaling pathways and is closely related to various tumorigenesis. Inhibition of the abnormal activity of SHP2 by small molecules is an important part of cancer treatment. Here, thre...

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Detalles Bibliográficos
Autores principales: Yan, Hongling, Jiang, Miao, Yang, Fujin, Tang, Xueyong, Lin, Mao, Zhou, Chunyan, Tan, Yuzhu, Liu, Deming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457730/
https://www.ncbi.nlm.nih.gov/pubmed/36080236
http://dx.doi.org/10.3390/molecules27175469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457730/
https://www.ncbi.nlm.nih.gov/pubmed/36080236
http://dx.doi.org/10.3390/molecules27175469

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