Preparation and Characterization of Disulfiram and Beta Cyclodextrin Inclusion Complexes for Potential Application in the Treatment of SARS-CoV-2 via Nebulization

Disulfiram (DS), known as an anti-alcoholism drug, has shown a potent antiviral activity. Still, the potential clinical application of DS is limited by its low water solubility and rapid metabolism. Cyclodextrins (CDs) have been widely used to improve the solubility of drugs in water. In this study,...

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Detalles Bibliográficos
Autores principales: Pereira, Ana Maria, Kaya, Ayse, Alves, Dan, Ansari-Fard, Niusha, Tolaymat, Ibrahim, Arafat, Basel, Najlah, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457755/
https://www.ncbi.nlm.nih.gov/pubmed/36080368
http://dx.doi.org/10.3390/molecules27175600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457755/
https://www.ncbi.nlm.nih.gov/pubmed/36080368
http://dx.doi.org/10.3390/molecules27175600

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