Computer-Aided Drug Design Boosts RAS Inhibitor Discovery

The Rat Sarcoma (RAS) family (NRAS, HRAS, and KRAS) is endowed with GTPase activity to regulate various signaling pathways in ubiquitous animal cells. As proto-oncogenes, RAS mutations can maintain activation, leading to the growth and proliferation of abnormal cells and the development of a variety...

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Detalles Bibliográficos
Autores principales: Wang, Ge, Bai, Yuhao, Cui, Jiarui, Zong, Zirui, Gao, Yuan, Zheng, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457765/
https://www.ncbi.nlm.nih.gov/pubmed/36080477
http://dx.doi.org/10.3390/molecules27175710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457765/
https://www.ncbi.nlm.nih.gov/pubmed/36080477
http://dx.doi.org/10.3390/molecules27175710

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