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Comparison of LC-MS(3) and LC-MRM Method for Quantifying Voriconazole and Its Application in Therapeutic Drug Monitoring of Human Plasma

The TDM of voriconazole which exhibits wide inter-individual variability is indispensable for treatment in clinic. In this study, a method that high-performance liquid chromatography tandem mass spectrometry cubed (HPLC-MS(3)) is first built and validated to quantify voriconazole in human plasma. Th...

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Detalles Bibliográficos
Autores principales: Ren, Wenbo, Yin, Lei, Zhang, Gaixia, Zhai, Taiyu, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457787/
https://www.ncbi.nlm.nih.gov/pubmed/36080374
http://dx.doi.org/10.3390/molecules27175609