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Virtual Screening in the Identification of Sirtuins’ Activity Modulators

Sirtuins are NAD(+)-dependent deac(et)ylases with different subcellular localization. The sirtuins’ family is composed of seven members, named SIRT-1 to SIRT-7. Their substrates include histones and also an increasing number of different proteins. Sirtuins regulate a wide range of different processe...

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Detalles Bibliográficos
Autores principales: Abbotto, Elena, Scarano, Naomi, Piacente, Francesco, Millo, Enrico, Cichero, Elena, Bruzzone, Santina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457788/
https://www.ncbi.nlm.nih.gov/pubmed/36080416
http://dx.doi.org/10.3390/molecules27175641