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Virtual Screening in the Identification of Sirtuins’ Activity Modulators
Sirtuins are NAD(+)-dependent deac(et)ylases with different subcellular localization. The sirtuins’ family is composed of seven members, named SIRT-1 to SIRT-7. Their substrates include histones and also an increasing number of different proteins. Sirtuins regulate a wide range of different processe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457788/ https://www.ncbi.nlm.nih.gov/pubmed/36080416 http://dx.doi.org/10.3390/molecules27175641 |