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Multivalent Pyrrolidine Iminosugars: Synthesis and Biological Relevance

Recently, the strategy of multivalency has been widely employed to design glycosidase inhibitors, as glycomimetic clusters often induce marked enzyme inhibition relative to monovalent analogs. Polyhydroxylated pyrrolidines, one of the most studied classes of iminosugars, are an attractive moiety due...

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Detalles Bibliográficos
Autores principales: Wang, Yali, Xiao, Jian, Meng, Aiguo, Liu, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457877/
https://www.ncbi.nlm.nih.gov/pubmed/36080188
http://dx.doi.org/10.3390/molecules27175420