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Fast and Sensitive HPLC-ESI-MS/MS Method for Etoricoxib Quantification in Human Plasma and Application to Bioequivalence Study

Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. The objective of the current study was to develop a sensitive, fast and high-throughput HPLC-ESI-MS/MS method to measure etoricoxib levels in human plasma using a one-step methanol protein precipitation...

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Detalles Bibliográficos
Autores principales: Loh, Gabriel Onn Kit, Wong, Emily Yii Ling, Tan, Yvonne Tze Fung, Heng, Siew Chyee, Saaid, Mardiana, Cheah, Kit Yee, Mohd Sali, Nurul Diyana, Damenthi, Nair, Ng, Sharon Shi Min, Ming, Long Chiau, Peh, Kok Khiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457878/
https://www.ncbi.nlm.nih.gov/pubmed/36080473
http://dx.doi.org/10.3390/molecules27175706