mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity

Forkhead box O (FOXO) proteins are transcription factors involved in cancer and aging and their pharmacological manipulation could be beneficial for the treatment of cancer and healthy aging. FOXO proteins are mainly regulated by post-translational modifications including phosphorylation, acetylatio...

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Detalles Bibliográficos
Autores principales: Jimenez, Lucia, Amenabar, Carlos, Mayoral-Varo, Victor, Mackenzie, Thomas A., Ramos, Maria C., Silva, Andreia, Calissi, Giampaolo, Grenho, Inês, Blanco-Aparicio, Carmen, Pastor, Joaquin, Megías, Diego, Ferreira, Bibiana I., Link, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457944/
https://www.ncbi.nlm.nih.gov/pubmed/36080182
http://dx.doi.org/10.3390/molecules27175414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457944/
https://www.ncbi.nlm.nih.gov/pubmed/36080182
http://dx.doi.org/10.3390/molecules27175414

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