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mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity
Forkhead box O (FOXO) proteins are transcription factors involved in cancer and aging and their pharmacological manipulation could be beneficial for the treatment of cancer and healthy aging. FOXO proteins are mainly regulated by post-translational modifications including phosphorylation, acetylatio...
Autores principales: | Jimenez, Lucia, Amenabar, Carlos, Mayoral-Varo, Victor, Mackenzie, Thomas A., Ramos, Maria C., Silva, Andreia, Calissi, Giampaolo, Grenho, Inês, Blanco-Aparicio, Carmen, Pastor, Joaquin, Megías, Diego, Ferreira, Bibiana I., Link, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457944/ https://www.ncbi.nlm.nih.gov/pubmed/36080182 http://dx.doi.org/10.3390/molecules27175414 |
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