Evolution of Interferon-Gamma Aptamer with Good Affinity and Analytical Utility by a Rational In Silico Base Mutagenesis Post-SELEX Strategy

The Systematic Evolution of Ligands by EXponential enrichment (SELEX) is conventionally an effective method to identify aptamers, which are oligonucleotide sequences with desired properties to recognize targets specifically and sensitively. However, there are some inherent limitations, e.g., the los...

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Detalles Bibliográficos
Autores principales: Zhao, Lianhui, Wang, Qionglin, Yin, Yingai, Yang, Yan, Cui, Huifang, Dong, Yiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457990/
https://www.ncbi.nlm.nih.gov/pubmed/36080490
http://dx.doi.org/10.3390/molecules27175725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457990/
https://www.ncbi.nlm.nih.gov/pubmed/36080490
http://dx.doi.org/10.3390/molecules27175725

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