Design, Synthesis and Biological Evaluation of New Carbohydrate-Based Coumarin Derivatives as Selective Carbonic Anhydrase IX Inhibitors via “Click” Reaction

In this work, we designed a series of new carbohydrate-based coumarin carbonic anhydrase IX inhibitors by using 1,2,3-triazoles as linker. Next, these designed compounds were synthesized by the optimized one-pot click chemistry reaction condition. Subsequently, these target compounds were assayed fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Chu, Naying, Wang, Yitong, Jia, Hao, Han, Jie, Wang, Xiaoyi, Hou, Zhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458059/
https://www.ncbi.nlm.nih.gov/pubmed/36080232
http://dx.doi.org/10.3390/molecules27175464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458059/
https://www.ncbi.nlm.nih.gov/pubmed/36080232
http://dx.doi.org/10.3390/molecules27175464

Ejemplares similares