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Ni(II) Ions May Target the Entire Melatonin Biosynthesis Pathway—A Plausible Mechanism of Nickel Toxicity

Nickel is toxic to humans. Its compounds are carcinogenic. Furthermore, nickel allergy is a severe health problem that affects approximately 10–20% of humans. The mechanism by which these conditions develop remains unclear, but it may involve the cleavage of specific proteins by nickel ions. Ni(II)...

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Detalles Bibliográficos
Autores principales: Wezynfeld, Nina E., Bonna, Arkadiusz M., Płonka, Dawid, Bal, Wojciech, Frączyk, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458082/
https://www.ncbi.nlm.nih.gov/pubmed/36080347
http://dx.doi.org/10.3390/molecules27175582