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Piezo1 Mechano-Activation Is Augmented by Resveratrol and Differs between Colorectal Cancer Cells of Primary and Metastatic Origin

Cancer cells must survive aberrant fluid shear stress (FSS) in the circulation to metastasize. Herein, we investigate the role that FSS has on colorectal cancer cell apoptosis, proliferation, membrane damage, calcium influx, and therapeutic sensitization. We tested this using SW480 (primary tumor) a...

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Detalles Bibliográficos
Autores principales: Greenlee, Joshua D., Liu, Kevin, Lopez-Cavestany, Maria, King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458129/
https://www.ncbi.nlm.nih.gov/pubmed/36080197
http://dx.doi.org/10.3390/molecules27175430