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Ortho-Phosphinoarenesulfonamide-Mediated Staudinger Reduction of Aryl and Alkyl Azides

Conventional Staudinger reductions of organic azides are sluggish with aryl or bulky aliphatic azides. In addition, Staudinger reduction usually requires a large excess of water to promote the decomposition of the aza-ylide intermediate into phosphine oxide and amine products. To overcome the challe...

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Detalles Bibliográficos
Autores principales: Li, Xingzhuo, Wang, Zhenguo, Luo, Wenjun, Wang, Zixu, Yin, Keshu, Li, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458194/
https://www.ncbi.nlm.nih.gov/pubmed/36080474
http://dx.doi.org/10.3390/molecules27175707